Ask The DEA: Is is safe to mix MDMA (ecstasy, molly) with nitrous oxide?
Dear Reader: Nitrous oxide has a generally good safety profile by itself, but one possible concern comes to mind. Nitrous oxide depletes vitamin B12, a nutrient essential for brain health. As a result, heavy nitrous use can cause a sort of malnutrition that can be harmful to the brain. The solution is simply to take a B12 supplement.
That being said, I don't see any obvious unusual danger from combining MDMA (ecstasy, molly) with nitrous; it appears to fall into the same 'generally safe' category as marijuana. If I were using nitrous with MDMA in any significant amount I would add some B12 to the usual antioxidant (vitamin C and E) preloading routine.
As always, safer drug use means less drug use. Higher doses, more frequent use, and mixing drugs all generally increases the possibility of health problem.
Still Alive (7/2/16)
As Hunter S. Thompson may have once said, "You can turn your back on a person, but never turn your back on a drug web site, especially when its waving a razor sharp hunting knife in your eye."
Or something like that. At any rate, some small updates and improvements are coming. To you, the readers who have found my little project useful, I thank you for your patience. :-)
Well, I'm done rounding up research; about 500 documents in all, dripping with dense academic-speak, tables and charts. For science geeks, there's been some cool stuff in the past few years (like a researcher who threw ecstasy-fueled orgies for his lab mice to see if the drug would affect how easily they caught herpes from each other.) There seems to have been a lot of development in our understanding of how exactly drugs like MDMA release neurotransmitters, which is exciting. They don't seem to be much closer to cracking the neurotoxicity mechanism, though. So far I haven't seen anything that would invalidate the opinions and advice currently on this site, but everything is up for review.
Also missing is the yet-to-be-published results of the landmark MAPS study on using MDMA to treat post-traumatic stress disorder (the severe anxiety and other problems caused by violent crime, combat, etc.) By all accounts the results have been extremely positive, with most of the patients actually cured. Given that PTSD is one of the hardest psychological problems to treat and they specifically chose patients that conventional treatment had been unable to help, that's nothing short of miraculous. Barring something very unexpected, MDMA is well on its way to becoming a (very tightly controlled) prescription medication.
On a web technology note, I hope to eliminate the use of Flash on this site over the coming year, as well as standardize on H.264 for videos, embedded with HTML 5. Flash has always been a bit of a pig; there just weren't any good alternatives before. I'm changing the standard font as well to try to make it easier on the eyes.
Death and Taxes (3/8/2010)
As some smartass once observed, life is what happens while you're busy making other plans. Life...happened to me. Some good things, some bad things, but always the inescapable forward movement common to all humanity, much like a man falling to his death (whether death by old age or some more dramatic means.) I feel a little stupid right now; not so much in the usual metaphorical sense of being embarrassed (although there's a bit of that too for having let this site lay fallow for so long) so much as literally stupid. Several years of research in the field have gone by while I was distracted elsewhere. My knowledge has rusted a bit. (I find myself in the amusing position of re-reading my own web site to re-educate myself about what I once knew so well.)
It will likely be a while (months, at the least) before any significant movement happens with this site; there's too much to catch up on right now, and I still have many other demands on my time. But...I'm back.
To the people who have encouraged me to return to this rather strange project, I thank you.
Celebrating the Season: 12-24 (12/19/06)
Ah, the Christmas season, when millions
of people commemorate the birth of a Jewish messiah with ham dinners
and tree worship during the Winter Solstice*. If you aren't
particularly religious, there's still some reason to celebrate. On
Christmas Eve of 1912 the German pharmaceutical giant Merck filed a
patent for a new chemical: 3,4-methylenedioxymethamphetamine,
known today around the world as 'ecstasy'. Sadly, many decades
passed before it was discovered to be psychoactive. Had
they known, 1912 could have had a very merry holiday season indeed.
So, raise a toast to some long-dead
German chemists; MDMA turns 94 years old this Christmas Eve.
*Dec 25th was traditionally regarded as the winter solstice;
it actually occurs on the 22nd this year.
'Keep our Community Pure: Join the KKK!' (12/1/06)
We Love Japan! (And will burn in hell for it...) (10/17/06)
D.E.A. Agent Shoots Self in Foot, Sues (4/12/06)
The Strangely Silent Majority (4/4/06)
Peru: To Hell and Back (National Geographic) (3/6/06)
Why Whitey Don't Freeze (2/22/06)
A Force for Evil (1/18/06)
Tweakers...in Space! (10/18/05)
Official Web Site of the
US Government (6/6/05)
Ho Ho...Hmm. (12/19/04)
The cookie that bit back (10/18/04)
The $15,000,000 Man (4/11/04)
The Trouble with Democracy (2/28/04)
My Favorite Cowards (1/21/04)
A Useful Lie (11/21/03)
Mister, That Dog Ain't Right (11/05/03)
Rush To Judgment (10/11/03)
"Talk To Frank" Staff
Dumber Than Pithed Frogs (9/13/03)
DEA's Microgram Bulletin.
"Go not gentle
into that good night." (7/23/03)
Lax Canadian Laws Threaten US (6/27/03)
Your Dog on Drugs (6/16/03)
ASCII (text) Art Cows
(Not everything gets archived.)